Publications
Radford, F., Sapers, N., Burgess, H., Ort, L., Budnik, B., Church, G. (2026). Automated
Prototyping of Genetic codes. Nature, Aug 26:1-1.
Radford, F., Lee, J., Kim D. S., d’Aquino, A. E., Schepartz, A., Jewett, M.C.*, Isaacs, F.J.* (2026). Evolution of tethered ribosomes for multisite incorporation of abiological monomers. In submission.
Grome M. W., Nguyen M. T., Moonan D. W., Mohler K., Gurara K., Wang S., Hemez C.,
Stenton B. J., Cao Y., Radford F., Kornaj M., ... & Isaacs, F. J. (2025) Engineering a
genomically recoded organism with one stop codon. Nature. 13;639(8054):512-21.
Chiappino-Pepe A., Radford F., Budnik B., TasĖ§ H., Augustin T. L., Burgess H. M., Moret
M., Dharani A. M., Zheng Q., Fan W., Africawala M. M., ... & Church, G. (2024) Preventing
escape and malfunction of recoded cells due to tRNA base changes. bioRxiv. 19:2024-07,
Nature, in revisions.
Hemez, C., Mohler, K., Radford, F., Moen, J., Rinehart, J., Isaacs, F. J. (2024). Genomically recoded Escherichia coli with optimized functional phenotypes. bioRxiv. 2024- 08
Radford, F., Rinehart, J., Isaacs, F.J. (2023). Mapping the in vivo fitness landscape of a tethered ribosome. Science Advances, 28;9(17):eade8934
Radford, F., Elliott, S. D., Schepartz, A., Isaacs, F. J. (2022). Targeted editing and evolution of engineered ribosomes in vivo by filtered editing. Nature Communications, 13(1), 1-13.
Arrigucci, R., Bushkin, Y., Radford, F., Lakehal, K., Vir, P., Pine, R., Martin, D., Sugarman, J., Zhao, Y., Yap, G. S., Lardizabal, A. A., Tyagi, S., Gennaro, M. L. (2017). FISH-Flow, a protocol for the concurrent detection of mRNA and protein in single cells using fluorescence in situ hybridization and flow cytometry. Nature Protocols, 12(6), 1245-1260.
Radford, F., Tyagi, S., Gennaro, M. L., Pine, R., Bushkin, Y. (2016). Flow cytometric characterization of antigen-specific T cells based on RNA and its advantages in detecting infections and immunological disorders. Critical Reviews in Immunology, 36(5).
Bushkin, Y., Radford, F., Pine, R., Lardizabal, A., Mangura, B. T., Gennaro, M. L., Tyagi, S. (2015). Profiling T cell activation using single-molecule fluorescence in situ hybridization and flow cytometry. The Journal of Immunology, 194(2), 836-841.
Patents
Radford F. and Church GM. Compositions and methods of use for protein engineering. U.S. Patent Application, filed March 5, 2026.
Radford F. and Church GM. Orthogonal aminoacyl trna synthetase pairs for protein production. U.S. Patent Application, filed April 4, 2025.
Isaacs, F. J. and Radford, F. Composition and methods for targeted editing and evolution of repetitive genetic elements. U.S. Patent Application, filed October 20, 2021.